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Phenotypes Associated with This Genotype
Genotype
MGI:2670767
Allelic
Composition
Pafah1b1tm1Awb/Pafah1b1+
Ywhaetm1Awb/Ywhae+
Genetic
Background
either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * NIH Black Swiss)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pafah1b1tm1Awb mutation (0 available); any Pafah1b1 mutation (151 available)
Ywhaetm1Awb mutation (1 available); any Ywhae mutation (55 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• neuronal migration distances in the cortex and in the hippocampus are shorter than in mice heterozygous for only one of these two loci
• very severe abnormalities in pyramidal cell packing as compared to mice heterozygous at only one of these two loci

cellular
• neuronal migration distances in the cortex and in the hippocampus are shorter than in mice heterozygous for only one of these two loci


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory