Mouse Genome Informatics
cx
    Pafah1b1tm1Awb/Pafah1b1+
Ywhaetm1Awb/Ywhae+

either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * NIH Black Swiss)
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• neuronal migration distances in the cortex and in the hippocampus are shorter than in mice heterozygous for only one of these two loci
• very severe abnormalities in pyramidal cell packing as compared to mice heterozygous at only one of these two loci

cellular
• neuronal migration distances in the cortex and in the hippocampus are shorter than in mice heterozygous for only one of these two loci

Mouse Models of Human Disease
OMIM IDRef(s)
Lissencephaly 1; LIS1 607432 J:84075
Miller-Dieker Lissencephaly Syndrome; MDLS 247200 J:84075