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Phenotypes Associated with This Genotype
Genotype
MGI:2657281
Allelic
Composition
Zic3Bn/Zic3+
Genetic
Background
BNT/LeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zic3Bn mutation (2 available); any Zic3 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• abnormal organ position, found in more than 50% of Bn/Y males and 38% of carrier females

limbs/digits/tail
• fewer caudal vertebrae than normal
• variable and milder severity compared to homozygous females and hemizygous males (J:13124)
(J:14983)
(J:63168)
• one or more bends (J:13124)
(J:14983)
(J:63168)

skeleton
• fewer caudal vertebrae than normal

Mouse Models of Human Disease
OMIM ID Ref(s)
Heterotaxy, Visceral, 1, X-Linked; HTX1 306955 J:5776 , J:13124 , J:14983 , J:62608 , J:63168


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory