About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:2657159
Allelic
Composition		 Dnmt1tm3Jae/Dnmt1tm2Enl
Genetic
Background		 involves: 129S4/SvJae * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnmt1tm2Enl mutation (1 available); any Dnmt1 mutation (108 available)
Dnmt1tm3Jae mutation (1 available); any Dnmt1 mutation (108 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor incidence ( J:82979 )
• 80% developed aggressive thymic tumors by 4 to 8 months of age
• high frequency of chromosome 15 trisomy

growth/size/body
postnatal growth retardation ( J:82979 )
• neonates were approximately 70% the weight of Dnmt1tm2Enl heterozygotes

reproductive system
reproductive system phenotype ( J:82979 )
N
• mice were fertile

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory