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Phenotypes Associated with This Genotype
Genotype
MGI:2653500
Allelic
Composition		 Yy1tm1Yshi/Yy1+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Yy1tm1Yshi mutation (0 available); any Yy1 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
decreased embryo size ( J:57857 )
• incomplete penetrance, seen in ~25% of mixed strain heterozygotes

growth/size/body
decreased embryo size ( J:57857 )
• incomplete penetrance, seen in ~25% of mixed strain heterozygotes

nervous system
exencephaly ( J:57857 )
• incomplete penetrance, seen in ~25% of mixed strain heterozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory