Phenotypes Associated with This Genotype

Genotype
MGI:2652966

• Allelic Composition: Kitl^Sl-5R/Kitl^Sl-5R
• Genetic Background: C3.Cg-Kitl^Sl-5R

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:82263 )

• almost 25% of homozygotes live past P2, unlike age-matched Kitl^Sl-gb homozygotes

• however, no homozygotes survive beyond P6

perinatal lethality, incomplete penetrance ( J:82263 )

• only 70% of the expected numbers of homozygotes are observed at P1

hematopoietic system

low mean erythrocyte cell number ( J:82263 )

• at P1, mean peripheral RBC counts are reduced to only 17% of wild-type controls, similar to mean RBC counts seen in age-matched Kitl^Sl-gb homozygotes