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Phenotypes Associated with This Genotype
Genotype
MGI:2651593
Allelic
Composition		 Gpx4tm1Prol/Gpx4+
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpx4tm1Prol mutation (1 available); any Gpx4 mutation (80 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
increased mortality induced by gamma-irradiation ( J:82053 )
• reduced survival on mixed 129/Sv and C57BL/6 genetic background relative to control littermates

homeostasis/metabolism
increased mortality induced by gamma-irradiation ( J:82053 )
• reduced survival on mixed 129/Sv and C57BL/6 genetic background relative to control littermates

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory