Phenotypes for Trp53 Tsg101 MGI:2450866 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Trp53^tm1Tyj/Trp53^tm1Tyj Tsg101^tm1Mak/Tsg101^tm1Mak
Genetic Background	involves: 129P3/J * 129S2/SvPas * C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp53^tm1Tyj mutation (12 available); any Trp53 mutation (237 available)
Tsg101^tm1Mak mutation (0 available); any Tsg101 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:67553 )

• die between E8.5 and E10.5

embryo

decreased embryo size ( J:67553 )

• mutants are smaller than wild-type mice but larger than Tsg101^tm1Mak homozygous mutant mice at E8.5

growth/size/body

decreased embryo size ( J:67553 )

• mutants are smaller than wild-type mice but larger than Tsg101^tm1Mak homozygous mutant mice at E8.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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