Phenotypes for Apc Dcc MGI:2446655 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Apc^Min/Apc⁺ Dcc^tm1Wbg/Dcc⁺
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apc^Min mutation (12 available); any Apc mutation (156 available)
Dcc^tm1Wbg mutation (1 available); any Dcc mutation (76 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased intestinal adenoma incidence ( J:39765 )

• heterozygosity for the Dcc allele did not affect the polyp initiation or average size or morphology of the adenomas that occur in the Apc^Min heterozygous mice

digestive/alimentary system

increased intestinal adenoma incidence ( J:39765 )

• heterozygosity for the Dcc allele did not affect the polyp initiation or average size or morphology of the adenomas that occur in the Apc^Min heterozygous mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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