Mouse Genome Informatics
cx
    Abcb1atm1Bor/Abcb1atm1Bor
Npc1m1N/Npc1m1N

involves: 129/Ola * BALB/c
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• neurological symptoms apparent and progressive, beginning at ~ day 50 of life
• failed to care for pups (J:76395)

homeostasis/metabolism
• cholesterol accumulation in liver

reproductive system
N
• mice were fertile (J:76395)

liver/biliary system
• cholesterol accumulation in liver

Mouse Models of Human Disease
OMIM IDRef(s)
Niemann-Pick Disease, Type C1; NPC1 257220 J:76395