Phenotypes Associated with This Genotype

Genotype
MGI:2183152

• Allelic Composition: Evx1^tm1.1Gld/Evx1^tm1.1Gld
• Genetic Background: involves: 129S/SvEv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:89813 )

N • normal alternate right left pattern of motor activity in L2 and L5 motor roots is preserved

abnormal ventral interneuron 0 morphology ( J:70192 )

• abnormal interneurons: V0 interneurons adopt a V1 interneuron cell fate

• abnormal axonal projections: V0 interneurons fail to project commissural axons; instead they project ipsilateral axonal projections similar to V1 interneurons