Phenotypes Associated with This Genotype

Genotype
MGI:2178062

• Allelic Composition: Hoxd12^tm2Ddu/Hoxd12^tm2Ddu
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal internal anal sphincter morphology ( J:36770 )

• ill-formed internal anal sphincter

muscle

abnormal smooth muscle morphology ( J:36770 )

• marked disorganization of rectal muscle layers in the region of the internal anal sphincter, with an abnormally thin or degenerated outer muscle layer

abnormal internal anal sphincter morphology ( J:36770 )

• ill-formed internal anal sphincter

limbs/digits/tail

abnormal phalanx morphology ( J:36770 )

• minor reduction of the second phalange of digit V

brachydactyly ( J:47366 )

• some digital elements are slightly reduced compared to in wild-type mice

skeleton

abnormal phalanx morphology ( J:36770 )

• minor reduction of the second phalange of digit V