Phenotypes for Aplp1 Aplp2 MGI:2176991 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Aplp1^tm1Umu/Aplp1^tm1Umu Aplp2^tm1Dbo/Aplp2^tm1Dbo
Genetic Background	involves: 129/Sv * 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aplp1^tm1Umu mutation (0 available); any Aplp1 mutation (26 available)
Aplp2^tm1Dbo mutation (1 available); any Aplp2 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:65196 )

• no obvious defect detected grossly or microscopically

• mice were born at normal Mendelian frequency (29% of 171 animals), but no surviving double mutants were found at P1, indicating that a combined deficiency results in lethality within the first day after birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23