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Phenotypes Associated with This Genotype
Genotype
MGI:2176697
Allelic
Composition
Arnttm1Gonz/Arnttm1Gonz
Tg(Mx1-cre)1Cgn/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arnttm1Gonz mutation (0 available); any Arnt mutation (65 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• induction of Cyp1A1 and Cyp1a2 by TCDD is absent from the liver, in addition Cyp1a2 constitutive expression is decreased
• hepatic induction of Slc2a1, Aldoa, and Hmox1 by CoCl2, which mimics physiological hypoxia, is variably reduced


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory