Mouse Genome Informatics
ht
    Ptpn11tm1Rbn/Ptpn11+
involves: 129 * Black Swiss
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
normal phenotype
• heterozygotes show no significant differences in body weight, plasma insulin, glucose levels during fasting or after a glucose challenge, insulin-stimulated glucose uptake in soleus muscle and adipocytes, and insulin-inhibited lipolysis in adipocytes relative to wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Noonan Syndrome 1; NS1 163950 J:35137