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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Mnx1-Zfp106,-EGFP)2Blk
transgenic insertion 2, Brian L Black
MGI:6150003
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(Mnx1-Zfp106,-EGFP)2Blk/0
Zfp106tm1b(KOMP)Wtsi/Zfp106tm1b(KOMP)Wtsi
involves: C57BL/6N MGI:6150434


Genotype
MGI:6150434
cx1
Allelic
Composition
Tg(Mnx1-Zfp106,-EGFP)2Blk/0
Zfp106tm1b(KOMP)Wtsi/Zfp106tm1b(KOMP)Wtsi
Genetic
Background
involves: C57BL/6N
Cell Lines EPD0033_4_C03
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Mnx1-Zfp106,-EGFP)2Blk mutation (0 available)
Zfp106tm1b(KOMP)Wtsi mutation (0 available); any Zfp106 mutation (115 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• significant suppression of muscle wasting compared to Zfp106 knockout allele alone

behavior/neurological
• significant suppression of muscle wasting and of loss of grip strength compared to Zfp106 knockout allele alone

nervous system
• significant restoration of number of choline-acetyltransferase-positive motor neurons in spinal cord compared to Zfp106 knockout allele alone

growth/size/body
• significant suppression of muscle wasting compared to Zfp106 knockout allele alone





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory