Phenotypes associated with this allele

• Allele Symbol: Myl2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5629324
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myl2^tm1b(EUCOMM)Hmgu/Myl2^tm1b(EUCOMM)Hmgu	C57BL/6N-Myl2^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262951
ht2	Myl2^tm1b(EUCOMM)Hmgu/Myl2^+	C57BL/6N-Myl2^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262950

Genotype
MGI:6262951

hm1

• Allelic Composition: Myl2^{tm1b(EUCOMM)Hmgu}/Myl2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Myl2^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0819_1_A05

Data Sources

IMPC Data for Myl2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262950

ht2

• Allelic Composition: Myl2^{tm1b(EUCOMM)Hmgu}/Myl2⁺
• Genetic Background: C57BL/6N-Myl2^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0819_1_A05

Data Sources

IMPC Data for Myl2

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

IMPC - HMGU

integument

absent vibrissae ( J:211773 )

IMPC - HMGU