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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Asic1tm1.1Ccli
targeted mutation 1.1, Cheng-Chang Lien
MGI:5490899
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Asic1tm1.1Ccli/Asic1tm1.1Ccli
Tg(Nes-cre)1Kln/0 		involves: 129 * C57BL/6 * SJL MGI:5490900


Genotype
MGI:5490900
cn1
Allelic
Composition		 Asic1tm1.1Ccli/Asic1tm1.1Ccli
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129 * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Asic1tm1.1Ccli mutation (0 available); any Asic1 mutation (40 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:193892 )
N
• hippocampal long term potentiation is similar to controls
abnormal CNS synaptic transmission ( J:193892 )
• absence of ASIC-like currents in nucleated patches isolated from interneurons in stratum oriens alveus

behavior/neurological
behavior/neurological phenotype ( J:193892 )
N
• spatial memory and learning are similar to controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory