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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Il7rtm1.1Asin
targeted mutation 1.1, Alfred Singer
MGI:5468999
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
B2mtm1Unc/B2mtm1Unc
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 MGI:5469010
cn2
Il4ratm1Sz/Il4ratm1Sz
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0
involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6 MGI:5469008
cn3
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0
involves: 129S7/SvEvBrd * C57BL/6 MGI:5469007
cn4
Il15tm1Imx/Il15tm1Imx
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0
involves: 129S7/SvEvBrd * C57BL/6 MGI:5469009
cn5
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd4-cre)1Cwi/0
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 MGI:5469006


Genotype
MGI:5469010
cn1
Allelic
Composition
B2mtm1Unc/B2mtm1Unc
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0
Genetic
Background
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B2mtm1Unc mutation (38 available); any B2m mutation (116 available)
Il7rtm1.1Asin mutation (1 available); any Il7r mutation (19 available)
Il7rtm1Imx mutation (3 available); any Il7r mutation (19 available)
Tg(Cd8a*-cre)B8Asin mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system

hematopoietic system




Genotype
MGI:5469008
cn2
Allelic
Composition
Il4ratm1Sz/Il4ratm1Sz
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0
Genetic
Background
involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il4ratm1Sz mutation (2 available); any Il4ra mutation (28 available)
Il7rtm1.1Asin mutation (1 available); any Il7r mutation (19 available)
Il7rtm1Imx mutation (3 available); any Il7r mutation (19 available)
Tg(Cd8a*-cre)B8Asin mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• in the thymus, as in Il7rtm1.1Asin/Il7rtm1Imx Tg(Cd8a*-cre)#Asin mice

hematopoietic system
• in the thymus, as in Il7rtm1.1Asin/Il7rtm1Imx Tg(Cd8a*-cre)#Asin mice




Genotype
MGI:5469007
cn3
Allelic
Composition
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il7rtm1.1Asin mutation (1 available); any Il7r mutation (19 available)
Il7rtm1Imx mutation (3 available); any Il7r mutation (19 available)
Tg(Cd8a*-cre)B8Asin mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• in the thymus and periphery

hematopoietic system
• in the thymus and periphery




Genotype
MGI:5469009
cn4
Allelic
Composition
Il15tm1Imx/Il15tm1Imx
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd8a*-cre)B8Asin/0
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il15tm1Imx mutation (5 available); any Il15 mutation (29 available)
Il7rtm1.1Asin mutation (1 available); any Il7r mutation (19 available)
Il7rtm1Imx mutation (3 available); any Il7r mutation (19 available)
Tg(Cd8a*-cre)B8Asin mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• in the thymus and periphery, worse than in Il7rtm1.1Asin/Il7rtm1Imx Tg(Cd8a*-cre)#Asin mice

hematopoietic system
• in the thymus and periphery, worse than in Il7rtm1.1Asin/Il7rtm1Imx Tg(Cd8a*-cre)#Asin mice




Genotype
MGI:5469006
cn5
Allelic
Composition
Il7rtm1.1Asin/Il7rtm1Imx
Tg(Cd4-cre)1Cwi/0
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il7rtm1.1Asin mutation (1 available); any Il7r mutation (19 available)
Il7rtm1Imx mutation (3 available); any Il7r mutation (19 available)
Tg(Cd4-cre)1Cwi mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system

hematopoietic system





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/04/2022
MGI 6.17
The Jackson Laboratory