All Phenotypes Tmem67<b2b1163.1Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tmem67^b2b1163.1Clo
Bench to Bassinet Program (B2B/CVDC), subline 1163.1 Cecilia Lo
MGI:5433409

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem67^b2b1163.1Clo/Tmem67^b2b1163.1Clo	C57BL/6J-Tmem67^b2b1163.1Clo	MGI:5433489

Allelic Composition	Tmem67^b2b1163.1Clo/Tmem67^b2b1163.1Clo
Genetic Background	C57BL/6J-Tmem67^b2b1163.1Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem67^b2b1163.1Clo mutation (1 available); any Tmem67 mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 1163-006-NA displays malpositioned heart with interrupted aorta and DORV (confirmed by EFIC imaging)

cardiovascular system

interrupted aortic arch ( J:175213 )

double outlet right ventricle ( J:175213 )

atrioventricular septal defect ( J:175213 )

heart right ventricle hypoplasia ( J:175213 )

growth/size/body

polycystic kidney ( J:175213 )

heterotaxia ( J:175213 )

renal/urinary system

polycystic kidney ( J:175213 )

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
cystic kidney disease	DOID:2975		J:175213
visceral heterotaxy	DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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