All Phenotypes Met<tm1Ics> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Met^tm1Ics
targeted mutation 1, Mouse Clinical Institute
MGI:5285647

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Met^tm1Ics/Met^tm1Sst Tg(Nes-cre)1Kln/0	involves: 129P2/OlaHsd * C57BL/6 * SJL	MGI:5285658

Allelic Composition	Met^tm1Ics/Met^tm1Sst Tg(Nes-cre)1Kln/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Met^tm1Ics mutation (0 available); any Met mutation (82 available)
Met^tm1Sst mutation (1 available); any Met mutation (82 available)
Tg(Nes-cre)1Kln mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

decreased motor neuron number ( J:174591 )

• by P2 with no further reduction in adult mice

• lacZ+ motor neurons are reduced at P2 in C8 and T1 regions of the spinal cord

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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