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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd68tm1Shnd
targeted mutation 1, Christian Schindler
MGI:5285208
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd68tm1Shnd/Cd68tm1Shnd either: B6.129-Cd68tm1Shnd or (involves: 129S1/Sv * 129X1/SvJ) MGI:5285210


Genotype
MGI:5285210
hm1
Allelic
Composition		 Cd68tm1Shnd/Cd68tm1Shnd
Genetic
Background		 either: B6.129-Cd68tm1Shnd or (involves: 129S1/Sv * 129X1/SvJ)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd68tm1Shnd mutation (0 available); any Cd68 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal dendritic cell antigen presentation ( J:175275 )
• dendritic cells stimulated with 0.05 and 0.1 mg/ml ovalbumin exhibit enhanced antigen presenting activity compared with wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory