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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Birc3tm1Rbr
targeted mutation 1, Robert Brink
MGI:5013652
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Cd19tm1(cre)Cgn/Cd19+ 		involves: 129P2/OlaHsd * C57BL/6 * NZB MGI:5013716
cx2
 		Birc2tm1.1Rbr/Birc2tm1.1Rbr
Birc3tm1Rbr/Birc3tm1Rbr 		involves: BALB/cJ * C57BL/6 MGI:5319372
cx3
 		Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr 		involves: C57BL/6 MGI:5319371


Genotype
MGI:5013716
cn1
Allelic
Composition		 Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Cd19tm1(cre)Cgn/Cd19+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * NZB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Birc2tm1Rbr mutation (0 available); any Birc2 mutation (33 available)
Birc3tm1Rbr mutation (0 available); any Birc3 mutation (31 available)
Cd19tm1(cre)Cgn mutation (11 available); any Cd19 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:172843 )
N
• mice exhibit no differences in spleen or lymph node size or in the numbers or phenotype of the B cells within these peripheral lymphoid tissues compared with wild-type mice




Genotype
MGI:5319372
cx2
Allelic
Composition		 Birc2tm1.1Rbr/Birc2tm1.1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Genetic
Background		 involves: BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Birc2tm1.1Rbr mutation (0 available); any Birc2 mutation (33 available)
Birc3tm1Rbr mutation (0 available); any Birc3 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:182515 )
• mice are viable with no reproductive or developmental defects




Genotype
MGI:5319371
cx3
Allelic
Composition		 Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Birc2tm1Rbr mutation (0 available); any Birc2 mutation (33 available)
Birc3tm1Rbr mutation (0 available); any Birc3 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory