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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Mt1-CETP)#Tall
transgene insertion, Alan Tall
MGI:4941577
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Apoa1tm1Bres/Apoa1tm1Bres
Tg(Mt1-CETP)#Tall/0
involves: 129S4/SvJae * C57BL/6 * CBA/J MGI:4941578
cx2
Ldlrtm1Her/Ldlrtm1Her
Tg(APOC3)3707Bres/?
Tg(Mt1-CETP)#Tall/?
involves: 129S7/SvEvBrd * C57BL/6J * CBA/J MGI:4941579


Genotype
MGI:4941578
cx1
Allelic
Composition
Apoa1tm1Bres/Apoa1tm1Bres
Tg(Mt1-CETP)#Tall/0
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoa1tm1Bres mutation (0 available); any Apoa1 mutation (16 available)
Tg(Mt1-CETP)#Tall mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice exhibit a further 44% reduction in HDL-C levels compared to in Apoa1tm1Bres homozygotes




Genotype
MGI:4941579
cx2
Allelic
Composition
Ldlrtm1Her/Ldlrtm1Her
Tg(APOC3)3707Bres/?
Tg(Mt1-CETP)#Tall/?
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ldlrtm1Her mutation (19 available); any Ldlr mutation (76 available)
Tg(APOC3)3707Bres mutation (1 available)
Tg(Mt1-CETP)#Tall mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• cholesterol shifted from HDL to IDL-LDL and VLDL
• lowered by 79% on a normal diet
• lowered by 36% on a Western diet
• cholesterol shifted from HDL to IDL-LDL and VLDL
• cholesterol shifted from HDL to IDL-LDL and VLDL
• triglycerides shifted from VLDL to IDL-LDL and HDL





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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory