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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ugcgtm4Rlp
targeted mutation 4, Richard L Proia
MGI:4442647
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ugcgtm4Rlp/Ugcgtm4Rlp involves: 129S6/SvEvTac * C57BL/6 MGI:4442807
cn2
Ugcgtm4Rlp/Ugcgtm4Rlp
Tg(Nes-cre)1Kln/0
involves: 129S6/SvEvTac * C57BL/6 * SJL MGI:4442808
cn3
Ugcgtm1Rlp/Ugcgtm4Rlp
Tg(Nes-cre)1Kln/0
involves: 129S6/SvEvTac * C57BL/6 * SJL MGI:4442809


Genotype
MGI:4442807
hm1
Allelic
Composition
Ugcgtm4Rlp/Ugcgtm4Rlp
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ugcgtm4Rlp mutation (1 available); any Ugcg mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are viable




Genotype
MGI:4442808
cn2
Allelic
Composition
Ugcgtm4Rlp/Ugcgtm4Rlp
Tg(Nes-cre)1Kln/0
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Nes-cre)1Kln mutation (4 available)
Ugcgtm4Rlp mutation (1 available); any Ugcg mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• at 6 months
• aged mice exhibit a labored gait unlike wild-type mice

nervous system
• severe at 9 months
• increases with age




Genotype
MGI:4442809
cn3
Allelic
Composition
Ugcgtm1Rlp/Ugcgtm4Rlp
Tg(Nes-cre)1Kln/0
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Nes-cre)1Kln mutation (4 available)
Ugcgtm1Rlp mutation (0 available); any Ugcg mutation (3 available)
Ugcgtm4Rlp mutation (1 available); any Ugcg mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• at 6 months
• aged mice exhibit a labored gait unlike wild-type mice

nervous system
• severe at 9 months
• increases with age





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory