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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Wnt2btm1.1Eem
targeted mutation 1.1, Edward E Morrisey
MGI:4361157
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Wnt2btm1.1Eem/Wnt2btm1.1Eem involves: 129X1/SvJ * C57BL/6 MGI:4361160
cx2
 		Wnt2tm1.1(rtTA)Eem/Wnt2tm1.1(rtTA)Eem
Wnt2btm1.1Eem/Wnt2btm1.1Eem 		involves: 129X1/SvJ * C57BL/6 MGI:4361161


Genotype
MGI:4361160
hm1
Allelic
Composition		 Wnt2btm1.1Eem/Wnt2btm1.1Eem
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt2btm1.1Eem mutation (0 available); any Wnt2b mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:153098 )
• mice exhibit no discernable phenotype




Genotype
MGI:4361161
cx2
Allelic
Composition		 Wnt2tm1.1(rtTA)Eem/Wnt2tm1.1(rtTA)Eem
Wnt2btm1.1Eem/Wnt2btm1.1Eem
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt2btm1.1Eem mutation (0 available); any Wnt2b mutation (22 available)
Wnt2tm1.1(rtTA)Eem mutation (0 available); any Wnt2 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
absent lungs ( J:153098 )
• at E11.5 and E14.5, mice exhibit complete lung agenesis
absent trachea ( J:153098 )
• at E11.5 and E14.5, mice lack tracheal development




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory