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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nrastm1Mok
targeted mutation 1, Moyota Katsuki
MGI:3794957
Summary 15 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nrastm1Mok/Nrastm1Mok either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361199
hm2
Nrastm1Mok/Nrastm1Mok involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821334
cx3
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
B6.129S-Nrastm1Mok Krastm1Mok MGI:4821324
cx4
Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361200
cx5
Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361201
cx6
Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Krastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)7Mok/0
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) MGI:4361207
cx7
Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Tg(HRAS)2Jic/0
involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2 MGI:4821330
cx8
Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)2Jic/0
involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2 MGI:4821332
cx9
Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)2Jic/0
involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2 MGI:4821336
cx10
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821323
cx11
Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nras+
involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821328
cx12
Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821329
cx13
Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821331
cx14
Hrastm1Mok/Hras+
Nrastm1Mok/Nrastm1Mok
involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821333
cx15
Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
involves: 129S/SvEv * C57BL/6 * DBA/2 MGI:4821335


Genotype
MGI:4361199
hm1
Allelic
Composition
Nrastm1Mok/Nrastm1Mok
Genetic
Background
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• born in normal numbers
• are fertile
• no behavioral defects
• no spontaneous tumors




Genotype
MGI:4821334
hm2
Allelic
Composition
Nrastm1Mok/Nrastm1Mok
Genetic
Background
involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 2 of 237 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821324
cx3
Allelic
Composition
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Genetic
Background
B6.129S-Nrastm1Mok Krastm1Mok
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (36 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 19 of 26 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4361200
cx4
Allelic
Composition
Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
Genetic
Background
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (26 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• born in reduced numbers




Genotype
MGI:4361201
cx5
Allelic
Composition
Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
Genetic
Background
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (36 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most deaths occur between E18.5 and birth
• do not survive to weaning




Genotype
MGI:4361207
cx6
Allelic
Composition
Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Krastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)7Mok/0
Genetic
Background
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (26 available)
Krastm1Mok mutation (6 available); any Kras mutation (36 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
Tg(HRAS)7Mok mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• born in expected numbers




Genotype
MGI:4821330
cx7
Allelic
Composition
Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Tg(HRAS)2Jic/0
Genetic
Background
involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (26 available)
Krastm1Mok mutation (6 available); any Kras mutation (36 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
Tg(HRAS)2Jic mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• no mice exhibit chylous ascites




Genotype
MGI:4821332
cx8
Allelic
Composition
Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)2Jic/0
Genetic
Background
involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (26 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
Tg(HRAS)2Jic mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• no mice exhibit chylous ascites




Genotype
MGI:4821336
cx9
Allelic
Composition
Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
Tg(HRAS)2Jic/0
Genetic
Background
involves: 129S/SvEv * BALB/c * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (36 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
Tg(HRAS)2Jic mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• no mice exhibit chylous ascites




Genotype
MGI:4821323
cx10
Allelic
Composition
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Genetic
Background
involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (36 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 5 of 76 mice develop chylous ascites unlike wild-type mice

immune system
• in the small intestine




Genotype
MGI:4821328
cx11
Allelic
Composition
Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nras+
Genetic
Background
involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (26 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 2 of 175 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821329
cx12
Allelic
Composition
Hrastm1Mok/Hrastm1Mok
Krastm1Mok/Kras+
Nrastm1Mok/Nras+
Genetic
Background
involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (26 available)
Krastm1Mok mutation (6 available); any Kras mutation (36 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 35 of 37 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821331
cx13
Allelic
Composition
Hrastm1Mok/Hrastm1Mok
Nrastm1Mok/Nrastm1Mok
Genetic
Background
involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (26 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 64 of 137 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821333
cx14
Allelic
Composition
Hrastm1Mok/Hras+
Nrastm1Mok/Nrastm1Mok
Genetic
Background
involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Mok mutation (15 available); any Hras mutation (26 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 5 of 153 mice develop chylous ascites unlike wild-type mice




Genotype
MGI:4821335
cx15
Allelic
Composition
Krastm1Mok/Kras+
Nrastm1Mok/Nrastm1Mok
Genetic
Background
involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm1Mok mutation (6 available); any Kras mutation (36 available)
Nrastm1Mok mutation (7 available); any Nras mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 6 of 6 mice develop chylous ascites unlike wild-type mice





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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory