Phenotypes associated with this allele
Allelic Composition |
Nrastm1Mok/Nrastm1Mok
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Genetic Background |
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) |
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrastm1Mok mutation
(7 available);
any
Nras mutation
(44 available)
|
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normal phenotype
|
• born in normal numbers
• are fertile
• no behavioral defects
• no spontaneous tumors
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrastm1Mok mutation
(7 available);
any
Nras mutation
(44 available)
|
|
|
mortality/aging
|
• born in reduced numbers
|
Allelic Composition |
Krastm1Mok/Kras+ Nrastm1Mok/Nrastm1Mok
|
|
Genetic Background |
either: (involves: 129S/SvEv * C57BL/6) or (involves: 129S/SvEv * C57BL/6 * DBA/2) |
|
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mortality/aging
|
• most deaths occur between E18.5 and birth
|
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• do not survive to weaning
|
normal phenotype
|
• born in expected numbers
|
Allelic Composition |
Krastm1Mok/Kras+ Nrastm1Mok/Nras+
|
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Genetic Background |
involves: 129S/SvEv * C57BL/6 * DBA/2 |
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homeostasis/metabolism
immune system