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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rtn4rtm1Gogo
targeted mutation 1, Joseph A Gogos
MGI:3774128
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rtn4rtm1Gogo/Rtn4rtm1Gogo involves: 129 * C57BL/6J MGI:3806713
ht2
Rtn4rtm1Gogo/Rtn4r+ involves: 129 * C57BL/6J MGI:3806714


Genotype
MGI:3806713
hm1
Allelic
Composition
Rtn4rtm1Gogo/Rtn4rtm1Gogo
Genetic
Background
involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtn4rtm1Gogo mutation (0 available); any Rtn4r mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit normal startle response, conditioned fear responses, and working memory in addition to not displaying behavioral despair (J:130368)
• mice do not display schizophrenia-related behaviors (J:130368)
• mice exhibit normal startle response, conditioned fear responses, and working memory in addition to not displaying behavioral despair (J:130368)
• mice do not display schizophrenia-related behaviors (J:130368)
• mice exhibit reduced vertical rearing in an open field test compared to wild-type mice (J:130368)
• mice exhibit reduced vertical rearing in an open field test compared to wild-type mice (J:130368)
• mice travel reduced distances in an open field test compared to wild-type mice (J:130368)
• mice treated with an NMDA blocker (MK-801) exhibit decreased locomotor activity compared to similarly treated wild-type mice (J:130368)
• mice travel reduced distances in an open field test compared to wild-type mice (J:130368)
• mice treated with an NMDA blocker (MK-801) exhibit decreased locomotor activity compared to similarly treated wild-type mice (J:130368)

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Schizophrenia; SCZD 181500 J:130368




Genotype
MGI:3806714
ht2
Allelic
Composition
Rtn4rtm1Gogo/Rtn4r+
Genetic
Background
involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtn4rtm1Gogo mutation (0 available); any Rtn4r mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit normal startle response, conditioned fear responses, and working memory in addition to not displaying behavioral despair (J:130368)
• mice do not display schizophrenia-related behaviors (J:130368)
• mice exhibit normal startle response, conditioned fear responses, and working memory in addition to not displaying behavioral despair (J:130368)
• mice do not display schizophrenia-related behaviors (J:130368)
• mice exhibit reduced vertical rearing in an open field test compared to wild-type mice (J:130368)
• mice exhibit reduced vertical rearing in an open field test compared to wild-type mice (J:130368)
• mice travel reduced distances in an open field test compared to wild-type mice (J:130368)
• mice travel reduced distances in an open field test compared to wild-type mice (J:130368)





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory