All Phenotypes Agtpbp1<pcd-8J> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Agtpbp1^pcd-8J
Purkinje cell degeneration 8 Jackson
MGI:3772649

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Agtpbp1^pcd-8J/Agtpbp1^pcd-8J	BALB/cJ-Agtpbp1^pcd-8J/GrsrJ	MGI:3776121

Allelic Composition	Agtpbp1^pcd-8J/Agtpbp1^pcd-8J
Genetic Background	BALB/cJ-Agtpbp1^pcd-8J/GrsrJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtpbp1^pcd-8J mutation (0 available); any Agtpbp1 mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

ataxia ( J:132487 )

• moderate ataxia found by 3 to 4 weeks of age

growth/size/body

decreased body size ( J:132487 )

nervous system

decreased Purkinje cell number ( J:132487 )

reproductive system

• abnormal sperm in one 19 week old male

reduced female fertility ( J:132487 )

• females are very poor breeders

male infertility ( J:132487 )

• males do not breed

vision/eye

abnormal retina layer morphology ( J:132487 )

• thin retinal vessels found in one 4 month old female and low rod and cone detection in one 6 week old male

retina degeneration ( J:132487 )

cellular

• abnormal sperm in one 19 week old male

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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