All Phenotypes Tead4<tm1Hssk> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tead4^tm1Hssk
targeted mutation 1, Hiroshi Sasaki
MGI:3770620

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tead4^tm1Hssk/Tead4^tm1Hssk	either: (involves: C57BL/6 * CBA) or (involves: C57BL/6 * CBA * DBA)	MGI:5485031

Allelic Composition	Tead4^tm1Hssk/Tead4^tm1Hssk
Genetic Background	either: (involves: C57BL/6 * CBA) or (involves: C57BL/6 * CBA * DBA)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tead4^tm1Hssk mutation (1 available); any Tead4 mutation (75 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• no embryos are recovered at post-implantation stages

embryo

absent blastocoele ( J:130047 )

• embryos fail to form clear blastocoeles

• however, cell proliferation is normal

absent trophoblast giant cells ( J:130047 )

absent trophectoderm ( J:130047 )

• embryos fail to form trophectoderm

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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