All Phenotypes Foxp3<tm2Tch> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Foxp3^tm2Tch
targeted mutation 2, Talal A Chatila
MGI:3699400

Summary

2 genotypes

Allelic Composition	Foxp3^tm2Tch/Foxp3⁺
Genetic Background	C.129X1-Foxp3^tm2Tch

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp3^tm2Tch mutation (3 available); any Foxp3 mutation (55 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:120713 )

N	• females are phenotypically normal and indistinguishable from wild-type littermates • EGFP expression in cells concordant with Foxp3 expression allows the kinetics of regulatory T cell proliferation and localization during a primary immune response

Allelic Composition	Foxp3^tm2Tch/Y
Genetic Background	C.129X1-Foxp3^tm2Tch

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp3^tm2Tch mutation (3 available); any Foxp3 mutation (55 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:120713 )

N	• males are phenotypically normal and indistinguishable from wild-type littermates • EGFP expression in cells concordant with Foxp3 expression allows the kinetics of regulatory T cell proliferation and localization during a primary immune response

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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