About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pdia3tm1Gjh
targeted mutation 1, Gunter J Hammerling
MGI:3664742
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cd19tm1(cre)Cgn/Cd19+
Pdia3tm1Gjh/Pdia3tm1Gjh 		involves: 129P2/OlaHsd * C57BL/6 MGI:3702091


Genotype
MGI:3702091
cn1
Allelic
Composition		 Cd19tm1(cre)Cgn/Cd19+
Pdia3tm1Gjh/Pdia3tm1Gjh
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (11 available); any Cd19 mutation (56 available)
Pdia3tm1Gjh mutation (0 available); any Pdia3 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal B cell physiology ( J:112606 )
• naive B cells express 50% - 90% less H-2Kb and have decreased H-2Db expression
• however, B cell development, survival, and proliferative responses are similar to control mice and mice raise normal titers of IgG

hematopoietic system
abnormal B cell physiology ( J:112606 )
• naive B cells express 50% - 90% less H-2Kb and have decreased H-2Db expression
• however, B cell development, survival, and proliferative responses are similar to control mice and mice raise normal titers of IgG




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory