Phenotypes associated with this allele

• Allele Symbol: Pth1r^tm4Hmk
• Allele Name: targeted mutation 4, Henry M Kronenberg
• Allele ID: MGI:3628795
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pth1r^tm4Hmk/Pth1r^tm4Hmk	involves: 129S4/SvJae * C57BL/6	MGI:3639097

Genotype
MGI:3639097

hm1

• Allelic Composition: Pth1r^tm4Hmk/Pth1r^tm4Hmk
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal skeleton development ( J:108984 )

• exhibit abnormalities in embryonic endochondral bone development

• delays in both chondrocyte differentiation and subsequent vascular invasion and bone deposition were observed

• blood ionized calcium and serum phosphate of mutant mice at 4 and 8 weeks were normal

• homozygous mutants are viable, appear grossly normal, and are fertile