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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Artm2(AR)Dmr
targeted mutation 2, Diane M Robins
MGI:3628489
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Artm2(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6 MGI:3629752
ot2
Artm2(AR)Dmr/Y involves: 129S1/Sv * C57BL/6J MGI:3614473


Genotype
MGI:3629752
cx1
Allelic
Composition
Artm2(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Artm2(AR)Dmr mutation (1 available); any Ar mutation (17 available)
Tg(TRAMP)8247Ng mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• at 29 weeks of age, 52% of male transgenic mutant mice had a palpable tumor or had died due to prostate cancer, compared to wild-type transgenic mice, comparable to wild-type transgenic mice

reproductive system
• at 29 weeks of age, 52% of male transgenic mutant mice had a palpable tumor or had died due to prostate cancer, compared to wild-type transgenic mice, comparable to wild-type transgenic mice

tumorigenesis
• at 29 weeks of age, 52% of male transgenic mutant mice had a palpable tumor or had died due to prostate cancer, compared to wild-type transgenic mice, comparable to wild-type transgenic mice

Mouse Models of Human Disease
OMIM ID Ref(s)
Prostate Cancer 176807 J:108849




Genotype
MGI:3614473
ot2
Allelic
Composition
Artm2(AR)Dmr/Y
Genetic
Background
involves: 129S1/Sv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Artm2(AR)Dmr mutation (1 available); any Ar mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• exhibit normal fertility and normal testes





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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory