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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo
targeted mutation 2, Liqun Luo
MGI:3623346
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo/Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo involves: 129S1/Sv * 129X1/SvJ MGI:3665430
cn2
Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo/Gt(ROSA)26Sortm1(Notch3*)Sfr
Notch3tm1.1(cre/ERT2)Sat/Notch3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac MGI:5556107


Genotype
MGI:3665430
hm1
Allelic
Composition
Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo/Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo mutation (2 available); any Gt(ROSA)26Sor mutation (745 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• homozygous females have low fertility




Genotype
MGI:5556107
cn2
Allelic
Composition
Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo/Gt(ROSA)26Sortm1(Notch3*)Sfr
Notch3tm1.1(cre/ERT2)Sat/Notch3+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Notch3*)Sfr mutation (0 available); any Gt(ROSA)26Sor mutation (745 available)
Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo mutation (2 available); any Gt(ROSA)26Sor mutation (745 available)
Notch3tm1.1(cre/ERT2)Sat mutation (0 available); any Notch3 mutation (62 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• following 4 weeks of tamoxifen treatment clonal expansion of cre expressing cells is markedly reduced

cellular
• following 4 weeks of tamoxifen treatment clonal expansion of cre expressing cells is markedly reduced

integument
• following 4 weeks of tamoxifen treatment clonal expansion of cre expressing cells is markedly reduced





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory