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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Disc1tm1Kara
targeted mutation 1, Maria Karayiorgou
MGI:3623218
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Disc1tm1Kara/Disc1tm1Kara B6.129S6-Disc1tm1Kara MGI:3623253
ht2
Disc1tm1Kara/Disc1+ B6.129S6-Disc1tm1Kara MGI:3623286


Genotype
MGI:3623253
hm1
Allelic
Composition
Disc1tm1Kara/Disc1tm1Kara
Genetic
Background
B6.129S6-Disc1tm1Kara
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Disc1tm1Kara mutation (0 available); any Disc1 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• working memory measured by a delayed non-match to place task was impaired compared with wild-type litter-mate controls (J:107244)
• working memory measured by a delayed non-match to place task was impaired compared with wild-type litter-mate controls (J:107244)

Mouse Models of Human Disease
OMIM ID Ref(s)
Schizophrenia; SCZD 181500 J:107244




Genotype
MGI:3623286
ht2
Allelic
Composition
Disc1tm1Kara/Disc1+
Genetic
Background
B6.129S6-Disc1tm1Kara
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Disc1tm1Kara mutation (0 available); any Disc1 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• working memory measured by a delayed non-match to place task was impaired compared with wild-type litter-mate controls (J:107244)
• working memory measured by a delayed non-match to place task was impaired compared with wild-type litter-mate controls (J:107244)

Mouse Models of Human Disease
OMIM ID Ref(s)
Schizophrenia; SCZD 181500 J:107244





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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory