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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Zbtb33tm1.1Bird
targeted mutation 1, Adrian Bird
MGI:3612463
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Zbtb33tm1.1Bird/Zbtb33tm1.1Bird involves: 129P2/OlaHsd * C57BL/6 MGI:3613445
cx2
ApcMin/Apc+
Zbtb33tm1.1Bird/Y
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J MGI:3613447
ot3
Zbtb33tm1.1Bird/Y involves: 129P2/OlaHsd * C57BL/6 MGI:3613444


Genotype
MGI:3613445
hm1
Allelic
Composition
Zbtb33tm1.1Bird/Zbtb33tm1.1Bird
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zbtb33tm1.1Bird mutation (0 available); any Zbtb33 mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• homozygous female mice exhibit no overt phenotype and are fertile; no differences in blood cell composition are detectable




Genotype
MGI:3613447
cx2
Allelic
Composition
ApcMin/Apc+
Zbtb33tm1.1Bird/Y
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (154 available)
Zbtb33tm1.1Bird mutation (0 available); any Zbtb33 mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• life span of these animals is an average of 317 days; this is improved over ApcMin mice alone at an average of 217 days

neoplasm
• mice exhibit a similar number of intestinal tumors as compared to ApcMin mice
• tumors in doubly heterozygous mice significantly smaller at 180 days of age

digestive/alimentary system
• mice exhibit a similar number of intestinal tumors as compared to ApcMin mice




Genotype
MGI:3613444
ot3
Allelic
Composition
Zbtb33tm1.1Bird/Y
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zbtb33tm1.1Bird mutation (0 available); any Zbtb33 mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• hemizygous male mice exhibit no overt phenotype and are fertile; no differences in blood cell composition are detectable
• hemizygous ES cells exhibit no significant differences from controls in neural specificaton, viability or neuronal or glial cell differentiation





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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory