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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ppm1ftm1Dgen
targeted mutation 1, Deltagen
MGI:3604597
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ppm1ftm1Dgen/Ppm1ftm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606444
ht2
Ppm1ftm1Dgen/Ppm1f+ involves: 129P2/OlaHsd * C57BL/6 MGI:3606446


Genotype
MGI:3606444
hm1
Allelic
Composition
Ppm1ftm1Dgen/Ppm1ftm1Dgen
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppm1ftm1Dgen mutation (1 available); any Ppm1f mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no homozygous mice identified at weaning and the genotypic ratio suggests either embryonic or perinatal lethality




Genotype
MGI:3606446
ht2
Allelic
Composition
Ppm1ftm1Dgen/Ppm1f+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppm1ftm1Dgen mutation (1 available); any Ppm1f mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• exhibit an increase in total distance traveled during open field testing, indicating possible hyperactivity
• significant increase in latency to lick a hindpaw or jump during hot plate testing, indicating a possible increase in pain threshold

integument
• significant increase in latency to lick a hindpaw or jump during hot plate testing, indicating a possible increase in pain threshold





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory