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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Grm1tm1Dgen
targeted mutation 1, Deltagen
MGI:3604591
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Grm1tm1Dgen/Grm1tm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606471


Genotype
MGI:3606471
hm1
Allelic
Composition
Grm1tm1Dgen/Grm1tm1Dgen
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grm1tm1Dgen mutation (3 available); any Grm1 mutation (61 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygotes die before 90 days of age

behavior/neurological
• seen at 20 and 49 days of age
• at 20 days of age stumbling and paddling movements are seen and at 49 days of age homozygotes are uncoordinated
• seen at 49 days of age
• seen at 20 and 49 days of age
• een at 20 days of age

growth/size/body
• homozygotes are thin at 20 days of age and runted and thin at 49 days of age
• seen at 49 days of age

skeleton
• bone mineral content is reduced in female homozygotes
• bone mineral density is reduced in female homozygotes





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory