All Phenotypes Chrnb3<tm1Sfh> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Chrnb3^tm1Sfh
targeted mutation 1, Stephen F Heinemann
MGI:3032611

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chrnb3^tm1Sfh/Chrnb3^tm1Sfh	involves: 129X1/SvJ * C57BL/6	MGI:3032625

Allelic Composition	Chrnb3^tm1Sfh/Chrnb3^tm1Sfh
Genetic Background	involves: 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chrnb3^tm1Sfh mutation (0 available); any Chrnb3 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal startle reflex ( J:87972 )

• although the acoustic startle response itself was normal, prepulse inhibition of the acoustic startle response was reduced

hyperactivity ( J:87972 )

• higher levels of activity in open field tests

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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