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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
MitfMi-Crc
microphthalmia MRC Clinical Research Centre
MGI:2662140
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
MitfMi-Crc/MitfMi-Crc CBA/CaCrc MGI:2662939
ht2
MitfMi-Crc/Mitf+ CBA/CaCrc MGI:2662973


Genotype
MGI:2662939
hm1
Allelic
Composition
MitfMi-Crc/MitfMi-Crc
Genetic
Background
CBA/CaCrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfMi-Crc mutation (0 available); any Mitf mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• hairs have no pigment
• eyes show no pigment

craniofacial

reproductive system

skeleton

vision/eye
• eyes show no pigment
• eyelids do not open

integument
• hairs have no pigment

growth/size/body

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Waardenburg syndrome type 2A DOID:0110950 OMIM:193510
J:83500




Genotype
MGI:2662973
ht2
Allelic
Composition
MitfMi-Crc/Mitf+
Genetic
Background
CBA/CaCrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MitfMi-Crc mutation (0 available); any Mitf mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• some heterozygotes show white spotting on the belly but not on the head
• iris pigment is reduced

limbs/digits/tail

vision/eye
• iris pigment is reduced

integument
• some heterozygotes show white spotting on the belly but not on the head

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Waardenburg syndrome type 1 DOID:0110948 OMIM:193500
J:83500





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/13/2017
MGI 6.10
The Jackson Laboratory