About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ifnar1tm1Uka
targeted mutation 1, Ulrich Kalinke
MGI:2655303
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cd19tm1(cre)Cgn/Cd19+
Ifnar1tm1Uka/Ifnar1tm1Uka 		B6.129P2-Cd19tm1(cre)Cgn Ifnar1tm1Uka MGI:3829380


Genotype
MGI:3829380
cn1
Allelic
Composition		 Cd19tm1(cre)Cgn/Cd19+
Ifnar1tm1Uka/Ifnar1tm1Uka
Genetic
Background		 B6.129P2-Cd19tm1(cre)Cgn Ifnar1tm1Uka
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19tm1(cre)Cgn mutation (11 available); any Cd19 mutation (56 available)
Ifnar1tm1Uka mutation (0 available); any Ifnar1 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgG1 level ( J:129128 )
• serum IgG1 levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgG2a level ( J:129128 )
• serum IgG2a levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgG3 level ( J:129128 )
• serum IgG3 levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgM level ( J:129128 )
• serum IgM levels are markedly decreased compared to controls 10- days after immunization with soluble antigen + IFNalpha stimulation

hematopoietic system
decreased IgG1 level ( J:129128 )
• serum IgG1 levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgG2a level ( J:129128 )
• serum IgG2a levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgG3 level ( J:129128 )
• serum IgG3 levels are markedly decreased compared to controls 10- and 35- days after immunization with soluble antigen + IFNalpha stimulation
decreased IgM level ( J:129128 )
• serum IgM levels are markedly decreased compared to controls 10- days after immunization with soluble antigen + IFNalpha stimulation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory