Mouse Genome Informatics
ht1
    Rr27tm1Rohl/H19+
involves: 129S1/Sv * 129X1/SvJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
digestive/alimentary system
• mice have longer crypts than wild-type mice

endocrine/exocrine glands
• mice have longer crypts than wild-type mice


Mouse Genome Informatics
ht2
    Rr27tm1Rohl/H19+
involves: 129S1/Sv * 129X1/SvJ * FVB/N * SD7
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
growth/size
• when the allele is inherited maternally, neonatal weight is increased by 11%

cellular
• when the allele is inherited maternally, imprinting of Igf2 is lost


Mouse Genome Informatics
cx3
    ApcMin/ApcMin
Rr27tm1Rohl/H19+

involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
tumorigenesis
• mice develop twice as many colonic adenomas as in ApcMin homozygotes
• mice develop twice as many intestinal and colonic adenomas as in ApcMin homozygotes

digestive/alimentary system
• mice have longer crypts than wild-type mice

endocrine/exocrine glands
• mice have longer crypts than wild-type mice