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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fbxl3Ovtm
overtime
MGI:2449078
Summary 7 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fbxl3Ovtm/Fbxl3Ovtm BTBR T+ Itpr3tf/Itpr3tf-Fbxl3Ovtm/Nwu MGI:2661870
hm2
 		Fbxl3Ovtm/Fbxl3Ovtm involves: BTBR * C57BL/6J MGI:5484574
hm3
 		Fbxl3Ovtm/Fbxl3Ovtm involves: BTBR/J * C3H/HeJ * C57BL/6J MGI:3717257
ht4
 		Fbxl3Ovtm/Fbxl3+ BTBR T+ Itpr3tf/Itpr3tf-Fbxl3Ovtm/Nwu MGI:2661872
ht5
 		Fbxl3Gt(FHCRC-GT-S13-12G1)Sor/Fbxl3Ovtm involves: BTBR/J * C3H/HeJ * C57BL/6J MGI:3717258
cx6
 		Fbxl3Ovtm/Fbxl3Ovtm
Nr1d1tm1Schb/Nr1d1tm1Schb 		involves: 129S2/SvPas * BTBR MGI:5494574
cx7
 		Fbxl21Psttm/Fbxl21Psttm
Fbxl3Ovtm/Fbxl3Ovtm 		involves: BTBR * C57BL/6J MGI:5484573


Genotype
MGI:2661870
hm1
Allelic
Composition		 Fbxl3Ovtm/Fbxl3Ovtm
Genetic
Background		 BTBR T+ Itpr3tf/Itpr3tf-Fbxl3Ovtm/Nwu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3Ovtm mutation (1 available); any Fbxl3 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
prolonged circadian behavior period ( J:83419 )
• homozygous mutant mice display a longer free running period than that of wild-type mice (25.88 hrs vs.23.27 hrs 0.13 sd)




Genotype
MGI:5484574
hm2
Allelic
Composition		 Fbxl3Ovtm/Fbxl3Ovtm
Genetic
Background		 involves: BTBR * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3Ovtm mutation (1 available); any Fbxl3 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
prolonged circadian behavior period ( J:194037 )
• period length is 26 hr




Genotype
MGI:3717257
hm3
Allelic
Composition		 Fbxl3Ovtm/Fbxl3Ovtm
Genetic
Background		 involves: BTBR/J * C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3Ovtm mutation (1 available); any Fbxl3 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
prolonged circadian behavior period ( J:122872 )
• circadian period is extended to 26.2 hours compared to 25.8 in wild-type mice




Genotype
MGI:2661872
ht4
Allelic
Composition		 Fbxl3Ovtm/Fbxl3+
Genetic
Background		 BTBR T+ Itpr3tf/Itpr3tf-Fbxl3Ovtm/Nwu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3Ovtm mutation (1 available); any Fbxl3 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
prolonged circadian behavior period ( J:83419 )
• heterozygous mutant mice display a longer free running period than that of wild-type mice (23.97 hrs vs.23.27 hrs 0.13 sd)




Genotype
MGI:3717258
ht5
Allelic
Composition		 Fbxl3Gt(FHCRC-GT-S13-12G1)Sor/Fbxl3Ovtm
Genetic
Background		 involves: BTBR/J * C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3Gt(FHCRC-GT-S13-12G1)Sor mutation (1 available); any Fbxl3 mutation (41 available)
Fbxl3Ovtm mutation (1 available); any Fbxl3 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
prolonged circadian behavior period ( J:122872 )
• circadian period is extended similar to in Fbxl3Ovtm homozygotes




Genotype
MGI:5494574
cx6
Allelic
Composition		 Fbxl3Ovtm/Fbxl3Ovtm
Nr1d1tm1Schb/Nr1d1tm1Schb
Genetic
Background		 involves: 129S2/SvPas * BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl3Ovtm mutation (1 available); any Fbxl3 mutation (41 available)
Nr1d1tm1Schb mutation (1 available); any Nr1d1 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:194250 )
N
• 23.7 hour circadian rhythm is relatively normal




Genotype
MGI:5484573
cx7
Allelic
Composition		 Fbxl21Psttm/Fbxl21Psttm
Fbxl3Ovtm/Fbxl3Ovtm
Genetic
Background		 involves: BTBR * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl21Psttm mutation (1 available); any Fbxl21 mutation (25 available)
Fbxl3Ovtm mutation (1 available); any Fbxl3 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:194037 )
N
• circadian period is 23.16 hr similar to that in wild-type controls and significantly shorter than the predicted 24.4 hr of an additive effect




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory