Mouse Genome Informatics
hm1
    Hbb-artm2Mkg/Hbb-artm2Mkg
involves: 129S4/SvJaeSor
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging
• death between E10.5 and E13.5
• death before development of appreciable numbers of erythrocytes appear

embryogenesis

hematopoietic system
• few erythroid cells at E12.5
• any erythrocytes found at E12.5 are immature
• poor hemoglobulin content of erythrocytes at E12.5
• evident at E12.5

cardiovascular system

growth/size/body

integument

Mouse Models of Human Disease
OMIM IDRef(s)
Beta-Thalassemia 613985 J:28981


Mouse Genome Informatics
ht2
    Hbb-artm2Mkg/Hbb-ar+
involves: 129S4/SvJaeSor
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
hematopoietic system
• anisopoikilocytosis, but otherwise normal RBCs