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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Hbb-artm2Mkg
targeted mutation 2, Mark Groudine
MGI:2445411
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Hbb-artm2Mkg/Hbb-artm2Mkg involves: 129S4/SvJaeSor MGI:2651679
ht2
Hbb-artm2Mkg/Hbb-ar+ involves: 129S4/SvJaeSor MGI:2673929


Genotype
MGI:2651679
hm1
Allelic
Composition
Hbb-artm2Mkg/Hbb-artm2Mkg
Genetic
Background
involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• death between E10.5 and E13.5
• death before development of appreciable numbers of erythrocytes appear

embryo

hematopoietic system
• few erythroid cells at E12.5
• any erythrocytes found at E12.5 are immature
• poor hemoglobulin content of erythrocytes at E12.5
• evident at E12.5

cardiovascular system

growth/size/body

integument

Mouse Models of Human Disease
OMIM ID Ref(s)
Beta-Thalassemia 613985 J:28981




Genotype
MGI:2673929
ht2
Allelic
Composition
Hbb-artm2Mkg/Hbb-ar+
Genetic
Background
involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• anisopoikilocytosis, but otherwise normal RBCs





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory