All Phenotypes T2dm2<C57BL/6J> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

T2dm2^C57BL/6J
C57BL/6J
MGI:2429604

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	T2dm2^C57BL/6J/T2dm2^C57BL/6J	BTBR.B6-T2dm2^C57BL/6J	MGI:3639671
cx2	Lep^ob/Lep^ob T2dm2^BTBR/T2dm2^C57BL/6J	involves: BTBR * C57BL/6J	MGI:3028548
cx3	Lep^ob/Lep^ob Stxbp5l^T2dm1/Stxbp5l^T2dm1 T2dm2^C57BL/6J/T2dm2^C57BL/6J	involves: BTBR * C57BL/6J	MGI:3028549

Allelic Composition	T2dm2^C57BL/6J/T2dm2^C57BL/6J
Genetic Background	BTBR.B6-T2dm2^C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased circulating insulin level ( J:109581 )

• females exhibit 30% reduction in fasting plasma insulin levels

Allelic Composition	Lep^ob/Lep^ob T2dm2^BTBR/T2dm2^C57BL/6J
Genetic Background	involves: BTBR * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lep^ob mutation (5 available); any Lep mutation (19 available)
T2dm2^BTBR mutation (0 available); any T2dm2 mutation (0 available)
T2dm2^C57BL/6J mutation (0 available); any T2dm2 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating insulin level ( J:65486 )

Allelic Composition	Lep^ob/Lep^ob Stxbp5l^T2dm1/Stxbp5l^T2dm1 T2dm2^C57BL/6J/T2dm2^C57BL/6J
Genetic Background	involves: BTBR * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lep^ob mutation (5 available); any Lep mutation (19 available)
Stxbp5l^T2dm1 mutation (0 available); any Stxbp5l mutation (60 available)
T2dm2^C57BL/6J mutation (0 available); any T2dm2 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

hyperglycemia ( J:65486 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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