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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Serpinf2tm1Hrl
targeted mutation 1, H Roger Lijnen
MGI:2181226
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Serpinf2tm1Hrl/Serpinf2tm1Hrl involves: 129X1/SvJ * C57BL/6J MGI:2672889


Genotype
MGI:2672889
hm1
Allelic
Composition
Serpinf2tm1Hrl/Serpinf2tm1Hrl
Genetic
Background
involves: 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Serpinf2tm1Hrl mutation (0 available); any Serpinf2 mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• higher frequency of spontaneous clot lysis (J:54047)
• less endotoxin induced fibrin deposition in the kidney (J:54047)
• cerebral ischemic infarct size is much smaller (J:55243)

Mouse Models of Human Disease
OMIM ID Ref(s)
Alpha-2-Plasmin Inhibitor Deficiency 262850 J:54047 , J:55243





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory