Phenotypes associated with this allele

• Allele Symbol: Syt4^tm1Hahe
• Allele Name: targeted mutation 1, Harvey R Herschman
• Allele ID: MGI:2180158
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Syt4^tm1Hahe/Syt4^tm1Hahe	involves: 129X1/SvJ * C57BL/6	MGI:2181815

Genotype
MGI:2181815

hm1

• Allelic Composition: Syt4^tm1Hahe/Syt4^tm1Hahe
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal contextual conditioning behavior ( J:62218 )

• in a foot shock test, homozygotes exhibited a deficit in freezing 24 hours after training compared to controls

impaired social transmission of food preference ( J:62218 )

• homozygous mice exhibit no preference for cued foods 24 hours after interaction with demonstrators; however, homozygotes did exhibit a preference immediately after interaction with demonstrators indicating that the initial learning of this task was not impaired

impaired coordination ( J:62218 )

• homozygous mice exhibit an impaired ability to remain on an accelerating rotarod compared to controls