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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Omptm1Mom
targeted mutation 1, Peter Mombaerts
MGI:2179520
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Ebf2tm2.1(Zfp423)Reed/Ebf2+
Omptm1Mom/Omp+
involves: 129S2/SvPas MGI:3714637
cx2
Omptm1Mom/Omp+
Zfp423tm1Reed/Zfp423tm1Reed
involves: 129S2/SvPas MGI:3714641
cx3
Adcy3tm1Drs/Adcy3tm1Drs
Omptm1Mom/Omp+
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 MGI:3714863


Genotype
MGI:3714637
cx1
Allelic
Composition
Ebf2tm2.1(Zfp423)Reed/Ebf2+
Omptm1Mom/Omp+
Genetic
Background
involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ebf2tm2.1(Zfp423)Reed mutation (0 available); any Ebf2 mutation (17 available)
Omptm1Mom mutation (2 available); any Omp mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• fewer number of mature olfactory receptor neurons

craniofacial
• fewer number of mature olfactory receptor neurons

respiratory system
• fewer number of mature olfactory receptor neurons

taste/olfaction
• fewer number of mature olfactory receptor neurons

growth/size/body
• fewer number of mature olfactory receptor neurons




Genotype
MGI:3714641
cx2
Allelic
Composition
Omptm1Mom/Omp+
Zfp423tm1Reed/Zfp423tm1Reed
Genetic
Background
involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Omptm1Mom mutation (2 available); any Omp mutation (22 available)
Zfp423tm1Reed mutation (0 available); any Zfp423 mutation (258 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• olfactory receptor neuron axons fail to innervate the dorsal caudal region of the olfactory bulb

craniofacial
• olfactory receptor neuron axons fail to innervate the dorsal caudal region of the olfactory bulb

respiratory system
• olfactory receptor neuron axons fail to innervate the dorsal caudal region of the olfactory bulb

taste/olfaction
• olfactory receptor neuron axons fail to innervate the dorsal caudal region of the olfactory bulb

growth/size/body
• olfactory receptor neuron axons fail to innervate the dorsal caudal region of the olfactory bulb




Genotype
MGI:3714863
cx3
Allelic
Composition
Adcy3tm1Drs/Adcy3tm1Drs
Omptm1Mom/Omp+
Genetic
Background
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adcy3tm1Drs mutation (0 available); any Adcy3 mutation (28 available)
Omptm1Mom mutation (2 available); any Omp mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• most glomeruli, including those in the necklace and Grueneberg, are reduced and loosely organized
• however, epithelia have normal amounts of mature olfactory sensory neurons
• from P15, Omp+ mature neurons are absent from the dorsocaudal part of the olfactory bulb





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last database update
01/04/2022
MGI 6.17
The Jackson Laboratory