Phenotypes associated with this allele

• Allele Symbol: Bmp7^tm2Rob
• Allele Name: targeted mutation 2, Elizabeth J Robertson
• Allele ID: MGI:2136986
• Summary: 4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bmp7^tm2Rob/Bmp7^tm2Rob	involves: 129S/SvEv	MGI:3629217
ht2	Bmp7^tm2Rob/Bmp7^tm4(Bmp4)Rob	involves: 129S/SvEv	MGI:3629218
ht3	Bmp7^tm2Rob/Bmp7^tm5(Bmp7/Bmp6)Rob	involves: 129S/SvEv	MGI:3629219
ht4	Bmp7^tm3(Bmp7)Rob/Bmp7^tm2Rob	involves: 129S/SvEv	MGI:3629220

Genotype
MGI:3629217

hm1

• Allelic Composition: Bmp7^tm2Rob/Bmp7^tm2Rob
• Genetic Background: involves: 129S/SvEv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

kidney cyst ( J:103587 )

• notable cyst formation is observed

abnormal kidney development ( J:103587 )

• paucity of nephrogenesis at the periphery is observed

hydroureter ( J:103587 )

growth/size/body

kidney cyst ( J:103587 )

• notable cyst formation is observed

Genotype
MGI:3629218

ht2

• Allelic Composition: Bmp7^tm2Rob/Bmp7^tm4(Bmp4)Rob
• Genetic Background: involves: 129S/SvEv

vision/eye

microphthalmia ( J:103587 )

• double mutants display bilateral microphthalmia at E14.5

Genotype
MGI:3629219

ht3

• Allelic Composition: Bmp7^tm2Rob/Bmp7^{tm5(Bmp7/Bmp6)Rob}
• Genetic Background: involves: 129S/SvEv

normal phenotype

no abnormal phenotype detected ( J:103587 )

Genotype
MGI:3629220

ht4

• Allelic Composition: Bmp7^tm3(Bmp7)Rob/Bmp7^tm2Rob
• Genetic Background: involves: 129S/SvEv

normal phenotype

no abnormal phenotype detected ( J:103587 )