hm1

Fbn2^fp/Fbn2^fp
C3Fe(B6)-Fbn2^fp/J

Key:
♀	phenotype observed in females	WTSI	Wellcome Trust Sanger Institute
♂	phenotype observed in males	Euro	Europhenome
N	normal phenotype

Limb clasping, reduced grip strength, and syndactyly in Fbn2^mz/Fbn2^mz, Fbn2^fp/Fbn2^fp and Fbn2^mz/Fbn2^fp mice

behavior/neurological

limb grasping ( J:157998 )

decreased grip strength ( J:157998 )

muscle

muscle weakness ( J:157998 )

limbs/digits/tail

syndactyly ( J:13514 , J:157998 )

• variable penetrance, usually of digits 2 and 3 or 3 and 4, more rarely 2, 3 and 4; more frequent incidence in hindpaws than forepaws (J:13514)

Mouse Models of Human Disease		OMIM ID	Ref(s)
NOT	Arthrogryposis, Distal, Type 9; DA9	121050	J:68881

ht2